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The force required to remove tubulin from the microtubule lattice by pulling on its α-tubulin C-terminal tail
Severing enzymes and molecular motors extract tubulin from the walls of microtubules by exerting mechanical force on subunits buried in the lattice. However, how much force is needed to remove tubulin from microtubules is not known, nor is the pathway by which subunits are removed. Using a site-spec...
Autores principales: | Kuo, Yin-Wei, Mahamdeh, Mohammed, Tuna, Yazgan, Howard, Jonathon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233703/ https://www.ncbi.nlm.nih.gov/pubmed/35752623 http://dx.doi.org/10.1038/s41467-022-31069-x |
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