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Structure‐function analysis for the development of peptide inhibitors for a Gram‐positive quorum sensing system
The Streptococcus pneumoniae Rgg144/SHP144 regulator‐peptide quorum sensing (QS) system is critical for nutrient utilization, oxidative stress response, and virulence. Here, we characterized this system by assessing the importance of each residue within the active short hydrophobic peptide (SHP) by...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233744/ https://www.ncbi.nlm.nih.gov/pubmed/35575437 http://dx.doi.org/10.1111/mmi.14921 |