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Structure‐function analysis for the development of peptide inhibitors for a Gram‐positive quorum sensing system

The Streptococcus pneumoniae Rgg144/SHP144 regulator‐peptide quorum sensing (QS) system is critical for nutrient utilization, oxidative stress response, and virulence. Here, we characterized this system by assessing the importance of each residue within the active short hydrophobic peptide (SHP) by...

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Detalles Bibliográficos
Autores principales: Abdullah, Iman Tajer, Ulijasz, Andrew T., Girija, Umakhanth Venkatraman, Tam, Sien, Andrew, Peter, Hiller, Natalia Luisa, Wallis, Russell, Yesilkaya, Hasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233744/
https://www.ncbi.nlm.nih.gov/pubmed/35575437
http://dx.doi.org/10.1111/mmi.14921

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