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Enhanced synergistic antitumor effect of a DNA vaccine with anticancer cytokine, MDA-7/IL-24, and immune checkpoint blockade

BACKGROUND: MDA-7/IL-24 cytokine has shown potent antitumor properties in various types of cancer without exerting any significant toxicity on healthy cells. It has also been proved to encompass pro-immune Th1 cytokine-like behavior. Several E7 DNA vaccines have developed against human papillomaviru...

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Detalles Bibliográficos
Autores principales: Miri, Seyed Mohammad, Pourhossein, Behzad, Hosseini, Seyed Younes, Keshavarz, Mohsen, Shahmahmoodi, Shohreh, Zolfaghari, Mohammad Reza, Mohebbi, Seyed Reza, Gorji, Ali, Ghaemi, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233788/
https://www.ncbi.nlm.nih.gov/pubmed/35752792
http://dx.doi.org/10.1186/s12985-022-01842-x