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Cell Line Characteristics Predict Subsequent Resistance to Androgen Receptor-Targeted Agents (ARTA) in Preclinical Models of Prostate Cancer

Treatment of prostate cancer (PCa) has changed considerably in the last decade due to the introduction of novel androgen receptor (AR)-targeted agents (ARTAs) for patients progressing on androgen deprivation therapy (ADT). Preclinical research however still relies heavily on AR-negative cell line mo...

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Detalles Bibliográficos
Autores principales: Moll, Jan Matthijs, Teubel, Wilma J., Erkens, Sigrun E., Jozefzoon-Agai, Ashraf, Dits, Natasja F., van Rijswijk, Angelique, Jenster, Guido W., van Weerden, Wytske M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234122/
https://www.ncbi.nlm.nih.gov/pubmed/35769712
http://dx.doi.org/10.3389/fonc.2022.877613