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Metformin, Rapamycin, or Nicotinamide Mononucleotide Pretreatment Attenuate Cognitive Impairment After Cerebral Hypoperfusion by Inhibiting Microglial Phagocytosis

Vascular cognitive impairment (VCI) is the second leading form of dementia after Alzheimer's disease (AD) plaguing the elder population. Despite the enormous prevalence of VCI, the biological basis of this disease has been much less well-studied than that of AD, with no specific therapy current...

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Detalles Bibliográficos
Autores principales: Yu, Mengdi, Zheng, Xiaoying, Cheng, Fangyu, Shao, Bei, Zhuge, Qichuan, Jin, Kunlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234123/
https://www.ncbi.nlm.nih.gov/pubmed/35769369
http://dx.doi.org/10.3389/fneur.2022.903565