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To Be or Not to Be: The Case of Endoplasmic Reticulum Aminopeptidase 2
To be, or not to be, that is the question. (William Shakespeare, Hamlet) Endoplasmic reticulum aminopeptidases 1 and 2 (ERAP1 and ERAP2, respectively) play a role in trimming peptides that are too long to be bound and presented by class I HLA (HLA-I) molecules to CD8(+) T cells. They may also affect...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234130/ https://www.ncbi.nlm.nih.gov/pubmed/35769458 http://dx.doi.org/10.3389/fimmu.2022.902567 |