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Oral Administration of a Shigella 2aT32-Based Vaccine Expressing UreB-HspA Fusion Antigen With and Without Parenteral rUreB-HspA Boost Confers Protection Against Helicobacter pylori in Mice Model

Helicobacter pylori (H. pylori) is a gram-negative pathogen classified as a class I carcinogen. The H. pylori urease B subunit (UreB) and heat shock protein A (HspA) are two important vaccine candidate antigens. In this study, we evaluated the immunogenicity and immunoprotective effect of the attenu...

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Detalles Bibliográficos
Autores principales: Zhang, Xin, Sang, Shuli, Guan, Qing, Tao, Haoxia, Wang, Yanchun, Liu, Chunjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234132/
https://www.ncbi.nlm.nih.gov/pubmed/35769459
http://dx.doi.org/10.3389/fimmu.2022.894206