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Efficacy of Candida dubliniensis and Fungal β-Glucans in Inducing Trained Innate Immune Protection Against Inducers of Sepsis

Fungal-bacterial intra-abdominal infections (IAI) can lead to sepsis with significant morbidity and mortality. We have established a murine model of Candida albicans (Ca) and Staphylococcus aureus (Sa) IAI that results in acute lethal sepsis. Prior intraperitoneal or intravenous inoculation with low...

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Detalles Bibliográficos
Autores principales: Harriett, Amanda J., Esher Righi, Shannon, Lilly, Elizabeth A., Fidel, Paul, Noverr, Mairi C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234138/
https://www.ncbi.nlm.nih.gov/pubmed/35770067
http://dx.doi.org/10.3389/fcimb.2022.898030