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The induction and inhibition of UDP-glycosyltransferases in Haemonchus contortus and their role in the metabolism of albendazole

Albendazole (ABZ) is an anthelmintic frequently used to treat haemonchosis, a common parasitosis of ruminants caused by the gastrointestinal nematode Haemonchus contortus. This parasite is able to protect itself against ABZ via the formation of inactive ABZ-glycosides. The present study was designed...

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Detalles Bibliográficos
Autores principales: Dimunová, Diana, Navrátilová, Martina, Kellerová, Pavlína, Ambrož, Martin, Skálová, Lenka, Matoušková, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234156/
https://www.ncbi.nlm.nih.gov/pubmed/35738156
http://dx.doi.org/10.1016/j.ijpddr.2022.06.001