Cargando…

The induction and inhibition of UDP-glycosyltransferases in Haemonchus contortus and their role in the metabolism of albendazole

Albendazole (ABZ) is an anthelmintic frequently used to treat haemonchosis, a common parasitosis of ruminants caused by the gastrointestinal nematode Haemonchus contortus. This parasite is able to protect itself against ABZ via the formation of inactive ABZ-glycosides. The present study was designed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dimunová, Diana, Navrátilová, Martina, Kellerová, Pavlína, Ambrož, Martin, Skálová, Lenka, Matoušková, Petra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Regular article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234156/ https://www.ncbi.nlm.nih.gov/pubmed/35738156 http://dx.doi.org/10.1016/j.ijpddr.2022.06.001

Ejemplares similares

UDP-Glycosyltransferases and Albendazole Metabolism in the Juvenile Stages of Haemonchus contortus
por: Kellerová, Pavlína, et al.
Publicado: (2020)

UDP-glycosyltransferase family in Haemonchus contortus: Phylogenetic analysis, constitutive expression, sex-differences and resistance-related differences
por: Matoušková, Petra, et al.
Publicado: (2018)

Sub-lethal doses of albendazole induce drug metabolizing enzymes and increase albendazole deactivation in Haemonchus contortus adults
por: Kellerová, Pavlína, et al.
Publicado: (2020)

Metabolism of albendazole, ricobendazole and flubendazole in Haemonchus contortus adults: Sex differences, resistance-related differences and the identification of new metabolites
por: Stuchlíková, Lucie Raisová, et al.
Publicado: (2018)

Sertraline as a new potential anthelmintic against Haemonchus contortus: toxicity, efficacy, and biotransformation
por: Zajíčková, Markéta, et al.
Publicado: (2021)

Anthelmintic activity of European fern extracts against Haemonchus contortus
por: Pavičić, Antonio, et al.
Publicado: (2023)

Short-chain dehydrogenases in Haemonchus contortus: changes during life cycle and in relation to drug-resistance
por: Štěrbová, Karolína, et al.
Publicado: (2023)

The ATP bioluminescence assay: a new application and optimization for viability testing in the parasitic nematode Haemonchus contortus
por: Nguyen, Linh Thuy, et al.
Publicado: (2021)

Image recognition based on deep learning in Haemonchus contortus motility assays
por: Žofka, Martin, et al.
Publicado: (2022)

The Identification of Metabolites and Effects of Albendazole in Alfalfa (Medicago sativa)
por: Raisová Stuchlíková, Lucie, et al.
Publicado: (2020)

Peptidomics of Haemonchus contortus
por: Buzy, Armelle, et al.
Publicado: (2021)

Arylpyrrole and fipronil analogues that inhibit the motility and/or development of Haemonchus contortus in vitro
por: Dilrukshi Herath, H.M.P., et al.
Publicado: (2018)

Phenotypic and genotypic analysis of benzimidazole resistance in reciprocal genetic crosses of Haemonchus contortus
por: Morrison, A.A., et al.
Publicado: (2021)

Allele specific PCR for a major marker of levamisole resistance in Haemonchus contortus
por: Antonopoulos, Alistair, et al.
Publicado: (2022)

Exploring benzimidazole resistance in Haemonchus contortus by next generation sequencing and droplet digital PCR
por: Baltrušis, Paulius, et al.
Publicado: (2018)

Genome-wide analysis of the response to ivermectin treatment by a Swedish field population of Haemonchus contortus
por: Baltrušis, Paulius, et al.
Publicado: (2021)

Identification and characterisation of the haemozoin of Haemonchus contortus
por: Liu, Lu, et al.
Publicado: (2023)

Assessing the Anthelmintic Candidates BLK127 and HBK4 for Their Efficacy on Haemonchus contortus Adults and Eggs, and Their Hepatotoxicity and Biotransformation
por: Zajíčková, Markéta, et al.
Publicado: (2022)

Similarities and differences in the biotransformation and transcriptomic responses of Caenorhabditis elegans and Haemonchus contortus to five different benzimidazole drugs
por: Stasiuk, S.J., et al.
Publicado: (2019)

Recent Research Progress in China on Haemonchus contortus
por: Wang, Chunqun, et al.
Publicado: (2017)

Dauer signalling pathway model for Haemonchus contortus
por: Ma, Guangxu, et al.
Publicado: (2019)

The presence and relative frequency detection of the levamisole-resistance-associated S168T substitution in hco-acr-8 in Haemonchus contortus
por: Baltrušis, Paulius, et al.
Publicado: (2023)

The Effects of Selected Sesquiterpenes from Myrica rubra Essential Oil on the Efficacy of Doxorubicin in Sensitive and Resistant Cancer Cell Lines
por: Ambrož, Martin, et al.
Publicado: (2017)

Antiproliferative Effects of Hop-derived Prenylflavonoids and Their Influence on the Efficacy of Oxaliplatine, 5-fluorouracil and Irinotecan in Human ColorectalC Cells
por: Ambrož, Martin, et al.
Publicado: (2019)

Resistance to experimental infections with Haemonchus contortus in Romanov sheep
por: Luffau, G, et al.
Publicado: (1990)

The genome and developmental transcriptome of the strongylid nematode Haemonchus contortus
por: Schwarz, Erich M, et al.
Publicado: (2013)

Inhibition of Haemonchus contortus larval development by fungal lectins
por: Heim, Christian, et al.
Publicado: (2015)

Reconstruction of the insulin-like signalling pathway of Haemonchus contortus
por: Mohandas, Namitha, et al.
Publicado: (2016)

Characterisation of P-glycoprotein-9.1 in Haemonchus contortus
por: Godoy, Pablo, et al.
Publicado: (2016)

Extreme-QTL mapping of monepantel resistance in Haemonchus contortus
por: Niciura, Simone Cristina Méo, et al.
Publicado: (2019)

Signatures of selection for resistance to Haemonchus contortus in sheep and goats
por: Estrada-Reyes, Zaira M., et al.
Publicado: (2019)

Transcriptomics and Proteomics of Haemonchus contortus in Response to Ivermectin Treatment
por: Liu, Yang, et al.
Publicado: (2023)

Structure-function and engineering of plant UDP-glycosyltransferase
por: Wang, Mengya, et al.
Publicado: (2023)

Development of a three-colour digital PCR for early and quantitative detection of benzimidazole resistance-associated single nucleotide polymorphisms in Haemonchus contortus
por: Hinney, Barbara, et al.
Publicado: (2023)

First report of anthelmintic resistance in Haemonchus contortus in alpacas in Australia
por: Jabbar, Abdul, et al.
Publicado: (2013)

In vitro anthelmintic efficacy of inhibitors of phosphoethanolamine Methyltransferases in Haemonchus contortus
por: Witola, William H., et al.
Publicado: (2016)

The cytochrome P450 family in the parasitic nematode Haemonchus contortus
por: Laing, Roz, et al.
Publicado: (2015)

In vitro potential anthelmintic activity of Biophytum petersianum on Haemonchus contortus
por: Sambodo, Priyo, et al.
Publicado: (2018)

Characterization of the development of Haemonchus contortus ZJ strain from gerbils
por: Yang, Yi, et al.
Publicado: (2017)

The Genome Sequence of the Anthelmintic-Susceptible New Zealand Haemonchus contortus
por: Palevich, Nikola, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_pmc0e5d316qr7alabgbi040n1g