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Differentiation of T Helper 17 Cells May Mediate the Abnormal Humoral Immunity in IgA Nephropathy and Inflammatory Bowel Disease Based on Shared Genetic Effects

BACKGROUND: IgA nephropathy (IgAN) is the most frequent glomerulonephritis in inflammatory bowel disease (IBD). However, the inter-relational mechanisms between them are still unclear. This study aimed to explore the shared gene effects and potential immune mechanisms in IgAN and IBD. METHODS: The m...

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Detalles Bibliográficos
Autores principales: Qing, Jianbo, Li, Changqun, Hu, Xueli, Song, Wenzhu, Tirichen, Hasna, Yaigoub, Hasnaa, Li, Yafeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234173/
https://www.ncbi.nlm.nih.gov/pubmed/35769467
http://dx.doi.org/10.3389/fimmu.2022.916934