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Integrating Metabolomics and Network Analysis for Exploring the Mechanism Underlying the Antidepressant Activity of Paeoniflorin in Rats With CUMS-Induced Depression

Background: Paeoniflorin (PF) represents the major bioactive constituent of the traditional Chinese medicine plant Paeonia suffruticosa (Ranunculaceae), which has a long history as a folk medicine in Asian. Paeoniflorin, a bitter pinene monoterpene glycoside, has antidepressant effects, but its pote...

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Detalles Bibliográficos
Autores principales: Lei, Chaofang, Chen, Zhigang, Fan, Lili, Xue, Zhe, Chen, Jianbei, Wang, Xihong, Huang, Zhen, Men, Yinian, Yu, Mingzhi, Liu, Yueyun, Chen, Jiaxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234202/
https://www.ncbi.nlm.nih.gov/pubmed/35770096
http://dx.doi.org/10.3389/fphar.2022.904190