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In vitro eradication of abasic site-mediated DNA–peptide/protein cross-links by Escherichia coli long-patch base excision repair

Apurinic/apyrimidinic (AP or abasic) sites are among the most abundant DNA lesions. Numerous proteins within different organisms ranging from bacteria to human have been demonstrated to react with AP sites to form covalent Schiff base DNA–protein cross-links (DPCs). These DPCs are unstable due to th...

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Detalles Bibliográficos
Autores principales: Bryan, Cameron, Wei, Xiaoying, Wang, Zhishuo, Yang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234237/
https://www.ncbi.nlm.nih.gov/pubmed/35605665
http://dx.doi.org/10.1016/j.jbc.2022.102055