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Coptidis Rhizoma Suppresses Metastatic Behavior by Inhibiting TGF-β-Mediated Epithelial-Mesenchymal Transition in 5-FU-Resistant HCT116 Cells

Colorectal cancer (CRC) is the second most lethal malignancy worldwide. The high mortality rate of CRC is largely due to cancer metastasis. Recently, suppressing epithelial-to-mesenchymal transition (EMT) has been considered a promising strategy for treating metastatic cancer, especially drug-resist...

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Detalles Bibliográficos
Autores principales: Kang, Yong-Hwi, Wang, Jing-Hua, Lee, Jin-Seok, Lee, Nam-Hun, Son, Chang-Gue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234293/
https://www.ncbi.nlm.nih.gov/pubmed/35770076
http://dx.doi.org/10.3389/fphar.2022.909331