Increased Expression of Mitochondrial UQCRC1 in Pancreatic Cancer Impairs Antitumor Immunity of Natural Killer Cells via Elevating Extracellular ATP

Pancreatic cancer (PC) is one of the most lethal malignancies characterized by a highly immunosuppressive tumor microenvironment (TME). Previously, we have reported that ubiquinol-cytochrome c reductase core protein I (UQCRC1), a key component of mitochondrial complex III, is generally upregulated i...

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Detalles Bibliográficos
Autores principales: Cong, Hui, Gao, Jian, Wang, Qing, Du, Min, Li, Huimin, Li, Qian, Li, Jin, Liang, Yiyi, Zhao, Dan, Yang, Hancao, Gan, Yu, Tu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234308/
https://www.ncbi.nlm.nih.gov/pubmed/35769718
http://dx.doi.org/10.3389/fonc.2022.872017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234308/
https://www.ncbi.nlm.nih.gov/pubmed/35769718
http://dx.doi.org/10.3389/fonc.2022.872017

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