A Review on Fused Pyrimidine Systems as EGFR Inhibitors and Their Structure–Activity Relationship

Epidermal growth factor receptor (EGFR) belongs to the family of tyrosine kinase that is activated when a specific ligand binds to it. The EGFR plays a vital role in the cellular proliferation process, differentiation, and apoptosis. In the case of cancer, EGFR undergoes uncontrolled auto-phosphoryl...

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Detalles Bibliográficos
Autores principales: Yadav, Tanuja T., Moin Shaikh, Gulam, Kumar, Maushmi S., Chintamaneni, Meena, YC, Mayur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234326/
https://www.ncbi.nlm.nih.gov/pubmed/35769445
http://dx.doi.org/10.3389/fchem.2022.861288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234326/
https://www.ncbi.nlm.nih.gov/pubmed/35769445
http://dx.doi.org/10.3389/fchem.2022.861288

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