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Effects of Intestinal FXR-Related Molecules on Intestinal Mucosal Barriers in Biliary Tract Obstruction

Background: The farnesoid X receptor (FXR) is a key factor regulating hepatic bile acid synthesis and enterohepatic circulation. Repression of bile acid synthesis by the FXR is a potential strategy for treating cholestatic liver disease. However, the role of intestinal FXR on the intestinal barrier...

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Detalles Bibliográficos
Autores principales: Yan, Meng, Hou, Li, Cai, Yaoyao, Wang, Hanfei, Ma, Yujun, Geng, Qiming, Jiang, Weiwei, Tang, Weibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234329/
https://www.ncbi.nlm.nih.gov/pubmed/35770078
http://dx.doi.org/10.3389/fphar.2022.906452