Celastrol inhibits the proliferation and migration of MCF-7 cells through the leptin-triggered PI3K/AKT pathway

Leptin is the pivotal modulator in the onset and progression of breast cancer and obesity. Celastrol, which is extracted from the roots of Tripterygium wilfordi plants, exerts various anticancer bioactivities and has recently emerged as a candidate to treat obesity by improving leptin sensitivity. H...

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Detalles Bibliográficos
Autores principales: Chen, Pingping, Wang, Bin, Li, Meng, Cui, Chunxue, Liu, Fei, Gao, Yonggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234344/
https://www.ncbi.nlm.nih.gov/pubmed/35782744
http://dx.doi.org/10.1016/j.csbj.2022.06.042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234344/
https://www.ncbi.nlm.nih.gov/pubmed/35782744
http://dx.doi.org/10.1016/j.csbj.2022.06.042

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