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Phosphorylation Induced Conformational Transitions in DNA Polymerase β

DNA polymerase β (pol β) is a member of the X- family of DNA polymerases that catalyze the distributive addition of nucleoside triphosphates during base excision DNA repair. Previous studies showed that the enzyme was phosphorylated in vitro with PKC at two serines (44 and 55), causing loss of DNA p...

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Detalles Bibliográficos
Autores principales: Srivastava, Amit, Idriss, Haitham, Taha, Kamal, Lee, Sungmun, Homouz, Dirar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234555/
https://www.ncbi.nlm.nih.gov/pubmed/35769908
http://dx.doi.org/10.3389/fmolb.2022.900771