A TNFR2-Specific TNF Fusion Protein With Improved In Vivo Activity

Tumor necrosis factor (TNF) receptor-2 (TNFR2) has attracted considerable interest as a target for immunotherapy. Indeed, using oligomeric fusion proteins of single chain-encoded TNFR2-specific TNF mutants (scTNF80), expansion of regulatory T cells and therapeutic activity could be demonstrated in v...

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Detalles Bibliográficos
Autores principales: Vargas, Juan Gamboa, Wagner, Jennifer, Shaikh, Haroon, Lang, Isabell, Medler, Juliane, Anany, Mohamed, Steinfatt, Tim, Mosca, Josefina Peña, Haack, Stephanie, Dahlhoff, Julia, Büttner-Herold, Maike, Graf, Carolin, Viera, Estibaliz Arellano, Einsele, Hermann, Wajant, Harald, Beilhack, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234581/
https://www.ncbi.nlm.nih.gov/pubmed/35769484
http://dx.doi.org/10.3389/fimmu.2022.888274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234581/
https://www.ncbi.nlm.nih.gov/pubmed/35769484
http://dx.doi.org/10.3389/fimmu.2022.888274

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