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Single‐cell transcriptomics reveals conserved cell identities and fibrogenic phenotypes in zebrafish and human liver

The mechanisms underlying liver fibrosis are multifaceted and remain elusive with no approved antifibrotic treatments available. The adult zebrafish has been an underutilized tool to study liver fibrosis. We aimed to characterize the single‐cell transcriptome of the adult zebrafish liver to determin...

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Detalles Bibliográficos
Autores principales: Morrison, Joshua K., DeRossi, Charles, Alter, Isaac L., Nayar, Shikha, Giri, Mamta, Zhang, Chi, Cho, Judy H., Chu, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234649/
https://www.ncbi.nlm.nih.gov/pubmed/35315595
http://dx.doi.org/10.1002/hep4.1930