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Molecular determinants of αVβ5 localization in flat clathrin lattices – role of αVβ5 in cell adhesion and proliferation

The vitronectin receptor integrin αVβ5 can reside in two distinct adhesion structures – focal adhesions (FAs) and flat clathrin lattices (FCLs). Here, we investigate the mechanism that regulates the subcellular distribution of β5 in keratinocytes and show that β5 has approximately 7- and 5-fold high...

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Detalles Bibliográficos
Autores principales: Zuidema, Alba, Wang, Wei, Kreft, Maaike, Bleijerveld, Onno B., Hoekman, Liesbeth, Aretz, Jonas, Böttcher, Ralph T., Fässler, Reinhard, Sonnenberg, Arnoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234671/
https://www.ncbi.nlm.nih.gov/pubmed/35532004
http://dx.doi.org/10.1242/jcs.259465