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Efficient silencing of hepatitis B virus S gene through CRISPR‐mediated base editing

Hepatitis B virus (HBV) infection is a major risk factor of liver cirrhosis and hepatocellular carcinoma. Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR‐associated protein 9 (Cas9) has been used to precisely edit the HBV genome and eliminate HBV through non‐homologous end‐...

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Detalles Bibliográficos
Autores principales:	Zhou, Hao, Wang, Xiaomei, Steer, Clifford J., Song, Guisheng, Niu, Junqi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234685/ https://www.ncbi.nlm.nih.gov/pubmed/35338607 http://dx.doi.org/10.1002/hep4.1933

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