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Integrins Cooperate With the EGFR/Ras Pathway to Preserve Epithelia Survival and Architecture in Development and Oncogenesis

Adhesion to the extracellular matrix (ECM) is required for normal epithelial cell survival. Disruption of this interaction leads to a specific type of apoptosis known as anoikis. Yet, there are physiological and pathological situations in which cells not connected to the ECM are protected from anoik...

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Detalles Bibliográficos
Autores principales: Valencia-Expósito, Andrea, Gómez-Lamarca, M. Jesús, Widmann, Thomas J., Martín-Bermudo, María D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234701/
https://www.ncbi.nlm.nih.gov/pubmed/35769262
http://dx.doi.org/10.3389/fcell.2022.892691