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Comparative analysis defines a broader FMRFamide-gated sodium channel family and determinants of neuropeptide sensitivity

FMRFamide (Phe-Met-Arg-Phe-amide, FMRFa) and similar neuropeptides are important physiological modulators in most invertebrates, but the molecular basis of FMRFa activity at its receptors is unknown. We therefore sought to identify the molecular determinants of FMRFa potency against one of its nativ...

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Detalles Bibliográficos
Autores principales: Dandamudi, Mowgli, Hausen, Harald, Lynagh, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234716/
https://www.ncbi.nlm.nih.gov/pubmed/35636513
http://dx.doi.org/10.1016/j.jbc.2022.102086