Dynamic spectrum of ectopic lymphoid B cell activation and hypermutation in the RA synovium characterized by NR4A nuclear receptor expression

Ectopic lymphoid structures (ELS) can develop in rheumatoid arthritis (RA) synovial tissue, but the precise pathways of B cell activation and selection are not well understood. Here, we identify a synovial B cell population characterized by co-expression of a family of orphan nuclear receptors (NR4A...

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Detalles Bibliográficos
Autores principales: Meednu, Nida, Rangel-Moreno, Javier, Zhang, Fan, Escalera-Rivera, Katherine, Corsiero, Elisa, Prediletto, Edoardo, DiCarlo, Edward, Goodman, Susan, Donlin, Laura T., Raychauduri, Soumya, Bombardieri, Michele, Pitzalis, Costantino, Orange, Dana E., McDavid, Andrew, Anolik, Jennifer H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234997/
https://www.ncbi.nlm.nih.gov/pubmed/35508128
http://dx.doi.org/10.1016/j.celrep.2022.110766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234997/
https://www.ncbi.nlm.nih.gov/pubmed/35508128
http://dx.doi.org/10.1016/j.celrep.2022.110766

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