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Computational exploration of maternal embryonic leucine zipper kinase (MELK) as a cancer drug target

Maternal embryonic leucine zipper kinase (MELK) is of vital importance due to its significant role in cancer development and its association with poor prognosis in different cancers. Here, we employed several computer aided drug design approaches to shortlist potential binding molecules of MELK. For...

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Detalles Bibliográficos
Autor principal: Makki Almansour, Nahlah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235044/
https://www.ncbi.nlm.nih.gov/pubmed/35769060
http://dx.doi.org/10.1016/j.sjbs.2022.103335