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Transient directing group enabled Pd-catalyzed C–H oxygenation of benzaldehydes and benzylic amines

We report a general protocol for <i>ortho</i>-C–H fluoroalkoxylation of benzaldehydes and benzylic amines utilizing an inexpensive amino amide as a transient directing group. In the presence of an electrophilic fluorinating bystanding oxidant and fluorinated alcohols, a wide range of ben...

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Detalles Bibliográficos
Autores principales: Tian, Mixiang, Shao, Lidong, Su, Xiaosan, Zhou, Xuhong, Zhang, Honglei, Wei, Kun, Sun, Ruifen, Wang, Junliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235058/
https://www.ncbi.nlm.nih.gov/pubmed/35873337
http://dx.doi.org/10.1039/d2ra00241h