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Characterization of gene cluster heterogeneity in single-cell transcriptomic data within and across cancer types

Despite the remarkable progress in probing tumor transcriptomic heterogeneity by single-cell RNA sequencing (sc-RNAseq) data, several gaps exist in prior studies. Tumor heterogeneity is frequently mentioned but not quantified. Clustering analyses typically target cells rather than genes, and differe...

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Detalles Bibliográficos
Autores principales: Tiong, Khong-Loon, Lin, Yu-Wei, Yeang, Chen-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235070/
https://www.ncbi.nlm.nih.gov/pubmed/35665803
http://dx.doi.org/10.1242/bio.059256