Cargando…

Targeting ferroptosis with miR-144-3p to attenuate pancreatic β cells dysfunction via regulating USP22/SIRT1 in type 2 diabetes

BACKGROUND: Recently, ferroptosis has been implicated in the pathologic process of several diseases including type 2 diabetes mellitus (T2DM). However, molecular mechanisms underlying ferroptosis in T2DM remain obscure. METHODS: Twenty four mice were included in this study. T2DM model mice were esta...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Shanshan, Liu, Xiao, Wang, Jihong, Yuan, Fengjuan, Liu, Yali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235078/
https://www.ncbi.nlm.nih.gov/pubmed/35761309
http://dx.doi.org/10.1186/s13098-022-00852-7