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TLR4 regulates RORγt(+) regulatory T-cell responses and susceptibility to colon inflammation through interaction with Akkermansia muciniphila

BACKGROUND: Well-balanced interactions between gut microbiota and the immune system are essential to prevent chronic intestinal inflammation, as observed in inflammatory bowel diseases (IBD). Toll-like receptor 4 (TLR4) functions as a sensor mediating the crosstalk between the intestinal commensal m...

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Detalles Bibliográficos
Autores principales: Liu, Yaojiang, Yang, Min, Tang, Li, Wang, Fengchao, Huang, Shengjie, Liu, Shuang, Lei, Yuanyuan, Wang, Sumin, Xie, Zhuo, Wang, Wei, Zhao, Xiaoyan, Tang, Bo, Yang, Shiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235089/
https://www.ncbi.nlm.nih.gov/pubmed/35761415
http://dx.doi.org/10.1186/s40168-022-01296-x