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Epigenetic DNA methylation of Zbtb7b regulates the population of double-positive CD4(+)CD8(+) T cells in ulcerative colitis

BACKGROUND AND AIMS: Ulcerative colitis (UC) is a heterogeneous disorder with complex pathogenesis. Therefore, in the present study, we aimed to assess genome-wide DNA methylation changes associated explicitly with the pathogenesis of UC. METHODS: DNA methylation changes were identified by comparing...

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Detalles Bibliográficos
Autores principales: Xu, Hao-ming, Xu, Jing, Yang, Mei-feng, Liang, Yu-jie, Peng, Quan-zhou, Zhang, Yuan, Tian, Cheng-mei, Nie, Yu-qiang, Wang, Li-sheng, Yao, Jun, Li, De-feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235105/
https://www.ncbi.nlm.nih.gov/pubmed/35761286
http://dx.doi.org/10.1186/s12967-022-03477-6