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WTAP-mediated N(6)-methyladenosine modification of NLRP3 mRNA in kidney injury of diabetic nephropathy

BACKGROUND: Diabetic nephropathy (DN) is prevalent in patients with diabetes. N(6)-methyladenosine (m(6)A) methylation has been found to cause modification of nucleotide-binding oligomerization domain, leucine-rich repeat, and pyrin domain-containing (NLRP) 3, which is involved in cell pyroptosis an...

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Detalles Bibliográficos
Autores principales: Lan, Jianzi, Xu, Bowen, Shi, Xin, Pan, Qi, Tao, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235192/
https://www.ncbi.nlm.nih.gov/pubmed/35761192
http://dx.doi.org/10.1186/s11658-022-00350-8