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WTAP-mediated N(6)-methyladenosine modification of NLRP3 mRNA in kidney injury of diabetic nephropathy
BACKGROUND: Diabetic nephropathy (DN) is prevalent in patients with diabetes. N(6)-methyladenosine (m(6)A) methylation has been found to cause modification of nucleotide-binding oligomerization domain, leucine-rich repeat, and pyrin domain-containing (NLRP) 3, which is involved in cell pyroptosis an...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235192/ https://www.ncbi.nlm.nih.gov/pubmed/35761192 http://dx.doi.org/10.1186/s11658-022-00350-8 |