A circular mRNA vaccine prototype producing VFLIP-X spike confers a broad neutralization of SARS-CoV-2 variants by mouse sera

Next-generation COVID-19 vaccines are critical due to the ongoing evolution of SARS-CoV-2 virus and rapid waning duration of the neutralizing antibody response against current vaccines. The mRNA vaccines mRNA-1273 and BNT162b2 were developed using linear transcripts encoding the prefusion-stabilized...

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Detalles Bibliográficos
Autores principales: Seephetdee, Chotiwat, Bhukhai, Kanit, Buasri, Nattawut, Leelukkanaveera, Puttipatch, Lerdwattanasombat, Pat, Manopwisedjaroen, Suwimon, Phueakphud, Nut, Kuhaudomlarp, Sakonwan, Olmedillas, Eduardo, Saphire, Erica Ollmann, Thitithanyanont, Arunee, Hongeng, Suradej, Wongtrakoongate, Patompon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235288/
https://www.ncbi.nlm.nih.gov/pubmed/35772601
http://dx.doi.org/10.1016/j.antiviral.2022.105370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235288/
https://www.ncbi.nlm.nih.gov/pubmed/35772601
http://dx.doi.org/10.1016/j.antiviral.2022.105370

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