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GH Responsiveness Is not Correlated to IGF1 P2 Promoter Methylation in Children With Turner Syndrome, GHD and SGA Short Stature

BACKGROUND: The methylation of IGF1 promoter P2 was reported to negatively correlate with serum IGF-1 concentration and rhGH treatment response in children with idiopathic short stature. These findings have not yet been confirmed. OBJECTIVE: This study aimed to determine IGF1 promoter P2 methylation...

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Detalles Bibliográficos
Autores principales: Apel, Anja, Iliev, Daniel I., Urban, Christina, Weber, Karin, Schweizer, Roland, Blumenstock, Gunnar, Pasche, Sarah, Nieratschker, Vanessa, Binder, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235359/
https://www.ncbi.nlm.nih.gov/pubmed/35769084
http://dx.doi.org/10.3389/fendo.2022.897897