Cargando…

Cross‐decoration of dendritic cells by non‐inherited maternal antigen‐containing extracellular vesicles: Potential mechanism for PD‐L1‐based tolerance in cord blood and organ transplantation

Exposure to non‐inherited maternal antigens (NIMA) during the fetal period induces lifelong split tolerance to grafts expressing these allo‐antigens. In adult mice, the production of extracellular vesicles (EVs) from maternal microchimeric cells causes cross‐decoration (XD) of offspring dendritic ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Lema, Diego A., Jankowska‐Gan, Ewa, Nair, Ashita, Kanaan, Sami B., Little, Christopher J., Foley, David P., Raza Naqvi, Afsar, Wang, Jianxin, Hong, Seungpyo, Nelson, J. Lee, Al‐Adra, David, Burlingham, William J., Sullivan, Jeremy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235410/
https://www.ncbi.nlm.nih.gov/pubmed/35143105
http://dx.doi.org/10.1111/ajt.16970