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Computing optimal factories in metabolic networks with negative regulation

MOTIVATION: A factory in a metabolic network specifies how to produce target molecules from source compounds through biochemical reactions, properly accounting for reaction stoichiometry to conserve or not deplete intermediate metabolites. While finding factories is a fundamental problem in systems...

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Detalles Bibliográficos
Autores principales: Krieger, Spencer, Kececioglu, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235471/
https://www.ncbi.nlm.nih.gov/pubmed/35758789
http://dx.doi.org/10.1093/bioinformatics/btac231