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Computing optimal factories in metabolic networks with negative regulation
MOTIVATION: A factory in a metabolic network specifies how to produce target molecules from source compounds through biochemical reactions, properly accounting for reaction stoichiometry to conserve or not deplete intermediate metabolites. While finding factories is a fundamental problem in systems...
Autores principales: | Krieger, Spencer, Kececioglu, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235471/ https://www.ncbi.nlm.nih.gov/pubmed/35758789 http://dx.doi.org/10.1093/bioinformatics/btac231 |
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