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Topsy-Turvy: integrating a global view into sequence-based PPI prediction

SUMMARY: Computational methods to predict protein–protein interaction (PPI) typically segregate into sequence-based ‘bottom-up’ methods that infer properties from the characteristics of the individual protein sequences, or global ‘top-down’ methods that infer properties from the pattern of already k...

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Detalles Bibliográficos
Autores principales: Singh, Rohit, Devkota, Kapil, Sledzieski, Samuel, Berger, Bonnie, Cowen, Lenore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235477/
https://www.ncbi.nlm.nih.gov/pubmed/35758793
http://dx.doi.org/10.1093/bioinformatics/btac258