PolarMorphism enables discovery of shared genetic variants across multiple traits from GWAS summary statistics

MOTIVATION: Pleiotropic SNPs are associated with multiple traits. Such SNPs can help pinpoint biological processes with an effect on multiple traits or point to a shared etiology between traits. We present PolarMorphism, a new method for the identification of pleiotropic SNPs from genome-wide associ...

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Detalles Bibliográficos
Autores principales: von Berg, Joanna, ten Dam, Michelle, van der Laan, Sander W, de Ridder, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
ISCB/Ismb 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235478/
https://www.ncbi.nlm.nih.gov/pubmed/35758773
http://dx.doi.org/10.1093/bioinformatics/btac228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235478/
https://www.ncbi.nlm.nih.gov/pubmed/35758773
http://dx.doi.org/10.1093/bioinformatics/btac228

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