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MeConcord: a new metric to quantitatively characterize DNA methylation heterogeneity across reads and CpG sites
MOTIVATION: Intermediately methylated regions occupy a significant fraction of the human genome and are closely associated with epigenetic regulations or cell-type deconvolution of bulk data. However, these regions show distinct methylation patterns, corresponding to different biological mechanisms....
Autores principales: | Zhang, Xianglin, Wang, Xiaowo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235486/ https://www.ncbi.nlm.nih.gov/pubmed/35758820 http://dx.doi.org/10.1093/bioinformatics/btac248 |
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