Do-calculus enables estimation of causal effects in partially observed biomolecular pathways

MOTIVATION: Estimating causal queries, such as changes in protein abundance in response to a perturbation, is a fundamental task in the analysis of biomolecular pathways. The estimation requires experimental measurements on the pathway components. However, in practice many pathway components are lef...

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Detalles Bibliográficos
Autores principales: Mohammad-Taheri, Sara, Zucker, Jeremy, Hoyt, Charles Tapley, Sachs, Karen, Tewari, Vartika, Ness, Robert, Vitek, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
ISCB/Ismb 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235495/
https://www.ncbi.nlm.nih.gov/pubmed/35758817
http://dx.doi.org/10.1093/bioinformatics/btac251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235495/
https://www.ncbi.nlm.nih.gov/pubmed/35758817
http://dx.doi.org/10.1093/bioinformatics/btac251

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