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Do-calculus enables estimation of causal effects in partially observed biomolecular pathways
MOTIVATION: Estimating causal queries, such as changes in protein abundance in response to a perturbation, is a fundamental task in the analysis of biomolecular pathways. The estimation requires experimental measurements on the pathway components. However, in practice many pathway components are lef...
Autores principales: | Mohammad-Taheri, Sara, Zucker, Jeremy, Hoyt, Charles Tapley, Sachs, Karen, Tewari, Vartika, Ness, Robert, Vitek, Olga |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235495/ https://www.ncbi.nlm.nih.gov/pubmed/35758817 http://dx.doi.org/10.1093/bioinformatics/btac251 |
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