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Bridging the gaps in statistical models of protein alignment

SUMMARY: Sequences of proteins evolve by accumulating substitutions together with insertions and deletions (indels) of amino acids. However, it remains a common practice to disconnect substitutions and indels, and infer approximate models for each of them separately, to quantify sequence relationshi...

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Detalles Bibliográficos
Autores principales: Sumanaweera, Dinithi, Allison, Lloyd, Konagurthu, Arun S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235498/
https://www.ncbi.nlm.nih.gov/pubmed/35758809
http://dx.doi.org/10.1093/bioinformatics/btac246