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DeepGOZero: improving protein function prediction from sequence and zero-shot learning based on ontology axioms

MOTIVATION: Protein functions are often described using the Gene Ontology (GO) which is an ontology consisting of over 50 000 classes and a large set of formal axioms. Predicting the functions of proteins is one of the key challenges in computational biology and a variety of machine learning methods...

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Detalles Bibliográficos
Autores principales: Kulmanov, Maxat, Hoehndorf, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235501/
https://www.ncbi.nlm.nih.gov/pubmed/35758802
http://dx.doi.org/10.1093/bioinformatics/btac256