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On the reliability and the limits of inference of amino acid sequence alignments

MOTIVATION: Alignments are correspondences between sequences. How reliable are alignments of amino acid sequences of proteins, and what inferences about protein relationships can be drawn? Using techniques not previously applied to these questions, by weighting every possible sequence alignment by i...

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Detalles Bibliográficos
Autores principales: Rajapaksa, Sandun, Sumanaweera, Dinithi, Lesk, Arthur M, Allison, Lloyd, Stuckey, Peter J, Garcia de la Banda, Maria, Abramson, David, Konagurthu, Arun S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235515/
https://www.ncbi.nlm.nih.gov/pubmed/35758808
http://dx.doi.org/10.1093/bioinformatics/btac247