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An isoxazole strategy for the synthesis of 4-oxo-1,4-dihydropyridine-3-carboxylates

A method has been developed for the preparation of 2-alkyl-6-aryl-, 2-aryl-6-aryl and 2,6-diaryl-5-aryl/hetaryl-substituted methyl 4-oxo-1,4-dihydropyridine-3-carboxylates by Mo(CO)(6)-mediated ring expansion of methyl 2-(isoxazol-5-yl)-3-oxopropanoates. The high reactivity of 4-oxo-1,4-dihydropyrid...

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Detalles Bibliográficos
Autores principales: Zanakhov, Timur O, Galenko, Ekaterina E, Novikov, Mikhail S, Khlebnikov, Alexander F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235835/
https://www.ncbi.nlm.nih.gov/pubmed/35821697
http://dx.doi.org/10.3762/bjoc.18.74