9p21.3 Microdeletion involving CDKN2A/2B in a young patient with multiple primary cancers and review of the literature

Germline pathogenic variants in CDKN2A predispose to various cancers, including melanoma, pancreatic cancer, and neural system tumors, whereas CDKN2B variants are associated with renal cell carcinoma. A few case reports have described heterozygous germline deletions spanning both CDKN2A and CDKN2B a...

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Detalles Bibliográficos
Autores principales: Jensen, Marlene Richter, Stoltze, Ulrik, Hansen, Thomas Van Overeem, Bak, Mads, Sehested, Astrid, Rechnitzer, Catherine, Mathiasen, René, Scheie, David, Larsen, Karen Bonde, Olsen, Tina Elisabeth, Muhic, Aida, Skjøth-Rasmussen, Jane, Rossing, Maria, Schmiegelow, Kjeld, Wadt, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235845/
https://www.ncbi.nlm.nih.gov/pubmed/35422439
http://dx.doi.org/10.1101/mcs.a006164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235845/
https://www.ncbi.nlm.nih.gov/pubmed/35422439
http://dx.doi.org/10.1101/mcs.a006164

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