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Structure of the human inner kinetochore CCAN complex and its significance for human centromere organization

Centromeres are specialized chromosome loci that seed the kinetochore, a large protein complex that effects chromosome segregation. A 16-subunit complex, the constitutive centromere associated network (CCAN), connects between the specialized centromeric chromatin, marked by the histone H3 variant CE...

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Detalles Bibliográficos
Autores principales: Pesenti, Marion E., Raisch, Tobias, Conti, Duccio, Walstein, Kai, Hoffmann, Ingrid, Vogt, Dorothee, Prumbaum, Daniel, Vetter, Ingrid R., Raunser, Stefan, Musacchio, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235857/
https://www.ncbi.nlm.nih.gov/pubmed/35525244
http://dx.doi.org/10.1016/j.molcel.2022.04.027