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Structure of the human inner kinetochore CCAN complex and its significance for human centromere organization
Centromeres are specialized chromosome loci that seed the kinetochore, a large protein complex that effects chromosome segregation. A 16-subunit complex, the constitutive centromere associated network (CCAN), connects between the specialized centromeric chromatin, marked by the histone H3 variant CE...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235857/ https://www.ncbi.nlm.nih.gov/pubmed/35525244 http://dx.doi.org/10.1016/j.molcel.2022.04.027 |